The Heartbreak of Recurrent Miscarriage - What Causes it and What to Do to preclude It

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Few things are more heartbreaking than a miscarriage. For many couples, as soon as the test is definite the tiny, few-day-old embryo is a person, and when the gravidity fails, the sense of loss is very real. An isolated miscarriage is a very common event, with 25% of recognized pregnancies ending in loss, so many if not most women will palpate a loss within their reproductive years. Less than 5% of women will palpate two consecutive miscarriages, and the number drops to less than 1% who palpate three or more.

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A concentrate who has experienced three or more losses may benefit from a thorough healing evaluation. This report will be the first of a three part series discussing the current healing knowledge about causes, tests and potential therapies for recurrent gravidity loss.

1. Genetic Causes

Sixty % or more of miscarriages are due to a random (by chance) chromosomal abnormality - usually a missing or duplicated chromosome in the fetus. The fetal or placental tissue can be obtained at the time of a miscarriage and tested for abnormalities. Unfortunately these types of problems are "accidents of nature", occurring when when the cells of an egg or sperm divide, and cannot be corrected. In the future, we may learn of a hereditary tendency for abnormal cell division.

Another type of chromosomal question occurs when one of the parents passes an abnormal number of genetic material to the embryo - a chromosome diagnosis done on the parents' blood can recognize this type of inherited genetic cause. Unbalanced translocation (part of one chromosome is attached to someone else one) is the most common inherited abnormality. To treat this question a concentrate may wish to reconsider in-vitro fertilization. Embryos obtained by Ivf can be tested through a procedure known as pre-implantation genetic diagnosis (Pgd), and only general embryos are then premium for transfer.

2. Age

For women over age 40 more than one-third of all pregnancies will end in a loss. The majority of the embryos lost, have an abnormal number of chromosomes. The intuit that age is such an foremost factor is that a woman is born with all of her eggs already stored in her ovaries. Thus, her eggs are field to all of the wear and tear that occurs in 40+ years. Recently some fairly dramatic advances have been made in the technology of icy ova (eggs). This may soon be widely ready to women who want to put off childbearing until mid-life. Egg donation is someone else alternative, already widely used. The risk of miscarriage linked with a donated egg is linked to the age of the egg donor not the recipient.

3. Male Factor

Increasing evidence suggests that the abnormal integrity (intactness) of sperm Dna may influence embryo amelioration and maybe increase miscarriage risk. definite medications such as sulfasalazine are very toxic to the male reproductive tract causing fragmentation in the chromosomes of the sperm. Testing being pioneered by Repromedix can detect Dna fragmentation levels; levels higher that 30% are linked with less than 1% chance of the female partner carrying a gravidity to term.

Couples who have experienced repeated miscarriages may benefit from counseling, as many are coping with grief, fear, anger, isolation, and helplessness. For more data and a maintain network, a very good site to visit is: recurrentmiscarriages.com.

Much of the data for this report was obtained from: Asrm.

With today's assisted reproductive technologies in conjunction with a salutary lifestyle, many couples will finally fulfill their dreams. Part two will discuss more causes, tests and therapies.

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